Takashi Miike's ALVIN AND THE CHIPMUNKS (2008):
A man named David Seville is married and his wife is pregnant, but his life is irrevocably changed when his wife gives birth to triplets. These triplets are horribly deformed and resemble Chipmunks more than humans, which when the mother sees her infant children, promptly dies. Struggling to raise them on his own, the kids eventually learn to talk in high pitched voices, and Seville finds a way to turn it around by teaching the boys how to make music. For some reason, these deformed children and their rock stylings sweep the nation. Hilarity ensues.